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Metabolic rate and energy expenditure: While AOD9604 mainly works through direct effects on fat cells, some research suggests it may also modestly increase metabolic rate and energy expenditure

Recent studies also suggest that 5-Amino-1MQ may hold promise in addressing the rejuvenation of senescent muscle stem cells, potentially contributing to enhanced muscle function and resilience as part of its multifaceted impact on longevity science

Studies have examined retatrutide in preclinical and clinical settings involving GLP-1, GIP, and glucagon receptor signaling and downstream metabolic endpoints

The compound's effects extend to muscle tissue, where NNMT inhibition modulates cellular energetics and contractile function