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The Potential Antidepressant Mechanisms of Acetyl-L-Carnitine About 2/3 of patients with severe depression are unable to achieve complete remission of symptoms with antidepressants currently available (74, 75)
Consequentially, if the SHBG is below 70 nmol/L in women or 25 nmol/L in men who are on thyroid replacement, the rest of body would not be expected to have adequate thyroid levels
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Neurosci ., 24 (4), 317326
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