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( C ) Schematic of IRI protocol and ( D ) percentage of LVDP recovery of isolated WT mouse hearts with the sAC inhibitor KH7 (20 mol/L) or the tmAC inhibitor Ddox (50 mol/L) prior to perfusion with buffer only (Cntl), scrambled(2836), GLP-1(2836), or GLP-1 ( n = 3/group)

References Fievet, C., Fruchart, J
Importantly, higher amounts of glucose ingested result in more incretin production, which results in more insulin release, more controlled reduction in blood glucose and a lower chance of developing rapid hypoglycemia

By advancing this field, we aim to inspire progress toward innovative treatments for these challenging conditions
