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Semaglutide has a cumulative exposure of over 22 million patient-years." "We will continue to invest in a variety of disease states including diabetes, chronic kidney disease, obesity, CV disease, liver disease, and Alzheimers disease, as seen in our robust clinical development programs and outcome studies," the statement continued

Antidepressants that modulate both serotonin and norepinephrine, including duloxetine and venlafaxine, appear to exert no significant influence on glucose regulation mechanisms [163]

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Small blood vessel disease of diabetes includes eye, kidney, and nerves of the feet