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doi: 10.1172/JCI112013

Species-specific action of (Pro3)GIP a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors

Moreover, because the TMD is less accessible than the extracellular region, this approach may facilitate the design of peptide ligands with moderate binding to better distinguish between target cells and nontarget cells

Small animal models of heart failure: development of novel therapies, past and present
