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[Abstract]2024;72(7):658-663
Metabolism and genetics Individual variations in GLP-1 receptor density and sensitivity affect how strongly any given dose activates the appetite suppression and glucose regulation pathways
Other GLP-1R/GIPR co-agonists such as Cpd86 (Eli Lilly), ZP-DI-70 (Zealand) and NN9709/MAR709 (Novo Nordisk/Marcadia) have also been designed and tested in preclinical models of obesity and subsequently advanced to clinical trials (Table 1)
