sulfonylurea vs glp 1 Drugs for Diabetes Mellitus Sulphonylureas in the management of

These medications work by mimicking the natural incretin hormone GLP-1, which stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and reduces appetite

Future research incorporating patients genomic information are expected to build better model

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The literature is conflicting on this topic, and although in vitro studies in obese mice have shown a positive effect of semaglutide in promoting muscle protein synthesis, increasing the relative proportion of skeletal muscle, and improving muscle function [119, 120], a synergistic dietary strategy such as the MD may help mitigate this concern and optimise the quality of weight loss