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Common gastrointestinal side effects include: Nausea (reported in up to 44% of patients) Diarrhoea (approximately 30% of patients) Vomiting (24% of patients) Constipation (around 24% of patients) Abdominal pain (approximately 20% of patients) Dyspepsia and gastro-oesophageal reflux Flatulence and abdominal distension These effects are typically most pronounced during the initial weeks of treatment and during dose escalation

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Kent S, Schlackow I, Lozano-Kuhne J, Reith C, Emberson J, Haynes R, Gray A, Cass A, Baigent C, Landray MJ, Herrington W, Mihaylova B, SHARP Collaborative Group

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Hayden Goldman (13:00): Absolutely

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