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Role of adiponectin and some other factors linking type 2 diabetes mellitus and obesity

LY3437943 has shown a powerful effect in reducing liver fat and liver injury markers in obese mice, which may be attributed to a combination of GCGR's direct impact on the liver or the indirect effects resulting from weight loss

Body weight was reduced with tirzepatide (0.9, 4.8, 8.7 and 11.3 kg for 1, 5, 10 and 15 mg, respectively) compared to a 2.7 kg reduction in weight by dulaglutide [129]

A goal of this advisory is to raise awareness and understanding of the role and importance of nutrition in health so that physicians can emphasize this to their patients and refer them to other members of the care team, such as registered dietitians, for thorough counseling