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Description
These trials followed patients receiving GLP-1 agents for several years while closely monitoring adverse events

Retrieved from Hale, P.M

Direct nutrient stimulation may induce the initial release of GLP-1 from small intestinal EECs, while large intestinal EECs likely release GLP-1 via a neural hormonal reflex or from microbe-derived metabolites, although this remains to be explored 93,99 (see the Gut microbiotabrain connection section)

doi: 10.1177/2045125316629071 56 GreenwayFLFujiokaKPlodkowskiRAMudaliarSGuttadauriaMEricksonJet al
