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Description
It increases the secretion of progesterone and estradiol in granulosa cells in response to stimulation by insulin-like growth factor-1 (IGF-1)
Currently in phase 3 clinical trials and due to be approved in 2026, orforglipron is being closely studied for its effectiveness and affordability
Ozempic, for example, is approved to treat type 2 diabetes but may be prescribed off-label for weight loss in adults
24 Similarly, it is prudent to prescribe ursodeoxycholic acid during the first year of GLP-1 receptor agonist therapy to prevent gallstone formation
