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Furthermore, with a run-in phase of a low-calorie diet, total weight loss of up to 12.5 kg can be achieved (of which half [6.2%] was observed during the liraglutide 3.0 mg treatment period) in subjects with obesity (176)

Understanding the full picture of peptide safety and risks applies here as well, especially if you are using any additional compounds alongside your GLP-1 medication

Wegovy and metformin drug warnings Both Wegovy and metformin carry a risk of low blood sugar levels, especially when used with insulin or insulin-boosting drugs

Pricing (as of April 2026): Compounded semaglutide: $179 to $279 per month depending on dose Compounded tirzepatide: $229 to $349 per month depending on dose Includes provider consultation, prescription, medication, and shipping How it works: Complete an online intake form and medical history Video consultation with a licensed Illinois provider (usually scheduled within 48 hours) If appropriate, the provider writes a prescription for compounded semaglutide or tirzepatide Medication is prepared by a state-licensed 503A compounding pharmacy and shipped to your address Monthly follow-up visits to adjust dose and monitor side effects Who this makes sense for: Patients denied prior authorization who don't want to appeal Patients who don't meet Illinois Medicaid's BMI criteria (for example, BMI 28 without comorbidities) Patients who want to start treatment immediately without waiting for step therapy Patients who prefer a flexible dosing schedule not available with FDA-approved products Who should pursue Illinois Medicaid coverage instead: Patients who meet BMI and comorbidity criteria and have a provider willing to complete prior authorization paperwork Patients who have already completed step therapy requirements Patients for whom $179 to $349 per month is not affordable The decision is patient-specific