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The newest exciting development in the way of medical therapy for HFpEF has been medications that target obesity such as incretin mimetic-based therapies including GLP1 receptor agonists

For a deeper background on the molecule and common brand contexts, see Semaglutide Uses and Dosage

This pattern mirrors other real-world reports showing that discontinuation of semaglutide often leads to partial or full weight regain, emphasizing the chronic nature of obesity and the pharmacologic principle that treatment efficacy is contingent upon sustained use [24]

The stall reflects a new equilibrium between these pharmaceutical effects and your body counterregulatory forces