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For individuals with diabetes and overweight or obesity, the ADA recommends as preferred pharmacotherapy a GLP-1 receptor agonist or a dual GLP-1/GIP receptor agonist with substantial weight-loss efficacy, meaning semaglutide or tirzepatide

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Patients generally find relief by: Eating smaller, more frequent meals rather than large portions Choosing bland, easily digestible foods during periods of nausea Avoiding high-fat, greasy, or spicy foods that may exacerbate symptoms Staying well-hydrated with water throughout the day Eating slowly and stopping when feeling comfortably satisfied Avoiding lying down immediately after eating For nausea management, some patients benefit from ginger tea, crackers, or other traditional remedies for mild queasiness

Most researchers report that injections at this volume are nearly painless with a fine-gauge needle