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How Rybelsus Works and Potential Drug Interactions Rybelsus contains semaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist licensed for the treatment of type 2 diabetes mellitus

If you have cardiovascular risk factors such as high blood pressure, high cholesterol, or a history of heart disease, your healthcare provider may consider GLP-1 shots as part of your treatment plan to help reduce your risk of cardiovascular complications

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For a simple oral solid-dose drug, generic supply can ramp in months