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Introduction We dont think a lot about addiction here [] anything about health is not on our mind statement by a JUUL electronic cigarette engineer ( Since tobacco cigarette use continues to be a main cause of preventable death in the US and worldwide ( In adult tobacco smokers, electronic cigarettes have been shown to be beneficial as cessation aids, but ultimately, the scientific evidence has indicated limited efficacy to reduce tobacco use over the long-term ( Factors influencing electronic cigarette use Electronic cigarette harm perception A multitude of factors influence the likelihood to initiate electronic cigarette use ( The relationship between sociodemographic factors and electronic cigarette use in adolescents is well established

Literature Search To identify studies on the pharmacokinetic effects of NPs, an expert librarian conducted a comprehensive, peer reviewed search across several databases March 13, 2024 (updated September 8, 2025): Scopus, Medline, Cochrane Central Register of Controlled Trials, EMBASE(McGowan et al., 2016)