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Several upregulated metabolites, such as D-homocysteine and 4-oxoproline, are relatively understudied in bacteria, and their precise roles remain unclear

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[45] demonstrated that the receptor for activated C kinase 1 (RACK1) protein interacted with InsR/IGF-1R and STAT3, both in in vitro and in vivo conditions, and this interaction was required for the activation of STAT3