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doi:10.1001/jamaoto.2019.4312 Jung SY, Jung J, Byun JY, Park MS, Kim SH, Yeo SG

Role of neuropoietic cytokines in development and progression of diabetic polyneuropathy: from glucose metabolism to neurodegeneration

SLC7A11 deficiency accelerates the progression of high-fat diet-induced MASLD through ferroptosis induced by classical cystine/cysteine deficiency, while serine deficiency and consequent obstruction of de novo synthesis of cysteine are responsible for the progression of ferroptosis induced MAFLD in hepatic SLC7A11 overexpressing mice
