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PMID: 34053018
Salviolone protects against high glucose-induced proliferation, oxidative stress, inflammation and fibrosis of human renal mesangial cells by upregulating membrane metalloendopeptidase expression
High glucose environments promote ferroptosis by suppressing GPx4 activity and depleting glutathione, leading to accumulation of oxidized phospholipids and endothelial cell death [461]
