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Am J Hum Genet 59(2):475 Caron NS, Wright GE, Hayden MR
Overall, our results indicate a remarkable responsiveness of mammals to changes in sulfur amino-acid availabilitythe ability to decrease CDO activity and conserve Cys when Cys is scarce and to rapidly increase CDO activity and catabolize Cys to prevent cytotoxicity when Cys supply is abundant
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This might seem like an inefficient way to do things, using methylcobalamin just to donate its methyl group and then having to remethylate it
