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The combined treatment of MYCi975 and CB-839 almost completely inhibited lymph node metastasis, and the combined treatment also more strongly inhibited tumor metastasis than either inhibitor alone [75]

There is potential for these combined techniques to increase the precision and effectiveness of ferroptosis diagnosis in clinical settings
In the case of excessive ROS production, other redox-sensitive systems are affected, such as expression of endothelial nitric oxide synthase (eNOS) (4)

Additionally, research has shown that statins can enhance eNOS activity by decreasing the expression of the membrane protein caveolin-1, thereby disrupting its binding with endothelial eNOS in caveolae (Suh et al., 2010)
