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2012 GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes Cosmetics Study demonstrating GHK-Cu's regulation of antioxidant gene expression and copper-dependent protective mechanisms in skin tissue

[DOI] [PubMed] [Google Scholar] 163.Ertunc ME, Sikkeland J, Fenaroli F, Griffiths G, Daniels MP, Cao H, et al

The requirement for hospitalization and mechanical ventilation in patients with severe COVID-19 (mostly in high-risk groups, such as elderly individuals or those with comorbidities) caused acute strains on healthcare systems at the peak of the pandemic, thus leading to national lockdowns and vaccination programs

Puerarin mitigates ferroptosis by regulating iron-handling proteins, reducing lipid peroxidation via Nrf2 activation, and inhibiting COX-2, thereby protecting against iron overload-induced retinal degeneration [118]