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AIDS, 22 (14), 1719-1728

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Still, a percentage of pyruvate enters the mitochondria, and a great portion of citrate generated at the TCA cycle from this pyruvate will be secreted to the cytosol through the mitochondrial tricarboxylate carrier

For example, ailanthone blocks autophagy by upregulating growth arrest specific (GAS)5 via inhibition of up-frameshift protein 1-mediated nonsense-mediated mRNA decay, thereby inhibiting NSCLC proliferation (22)