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Description
This BMAd senescence helped to confer resistance to myeloma-targeting drugs, suggesting that BMAds can both fuel and sustain long-term tumor growth
Disorders of fatty acid oxidation and organic acidemias can lead to secondary carnitine deficiency by trapping free carnitine by conjugating it with acyl moieties which accumulate in these conditions
This is why patients experience severe post-exertional malaise (PEM)their cells literally lack the energetic currency required to recover from even minor physical or cognitive exertion
318, H1474h1486
