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This preliminary evidence suggests that the MD diet reduces disease severity, IR, and hyperandrogenemia in PCOS (224)
and Vilardell, J., "Regulated pre-mRNA splicing: the ghostwriter of the eukaryotic genome", Biochem
10.1097/00005344-199322008-00043 21 FalcettiE.HallS
Furthermore, tobacco smoke is one factor that significantly contributes to oxidative stress and, consequently, to changes in the epigenetic machinery involving methylation (Mecocci and Polidori, 2012)
