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Biol Psychiat 90:2834 [DOI] [PubMed] [Google Scholar] Hussain G et al (2018) Role of Plant Derived Alkaloids and Their Mechanism in Neurodegenerative Disorders

The half-life of T4 is very long, about 7 days, so a slow-release formulation is not needed

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Second, self-reported sleep measures were employed to determine sleep disorders, which may be affected by estimation bias, compared to more-objective measures such as actigraphy and polysomnography