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Description
The most important redox buffer in cells is the antioxidant glutathione (GSH), which converts into oxidized glutathione (GSSG) under oxidative stress

First, although it was a prospective multicenter trial, it was still a single-arm study without a placebo

Wagner, Environmental Sciences Europe 30, (2018)

FAT1 has been reported as an important factor causing dysregulation of the Hippo pathway 29