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Since B12 plays a role in energy metabolism, some people report feeling more alert after taking their supplement, though this effect is anecdotal and not scientifically established

In addition, it seems that NNMT plays different roles in aerobic and anaerobic energy metabolism
doi: 10.3390/ijms21030950 Pubmed Abstract CrossRef Google Scholar View reference in article 11 HannaMJaquaENguyenVClayJ

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