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In this study, B12 levels were 244 pmol/l or more in all patients at baseline, but in those who improved, B12 levels almost quadrupled, whilst in non-responders B12 levels went up by only 50%

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The researchers also noted a correlation between glutathione levels and disease activity, suggesting that increasing glutathione levels may help reduce lupus symptoms

Behav Brain Res 205:550558 Rahman I, Kode A, Biswas SK (2006) Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method