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World J Gastroenterol 24(48):54625476 Lojo N, Rasic Z, Zenko Sever A, Kolenc D, Vukusic D, Drmic D et al (2016) Effects of diclofenac, L-NAME, L-arginine, and pentadecapeptide BPC 157 on gastrointestinal, liver, and brain lesions, failed anastomosis, and intestinal adaptation deterioration in 24 hour-short-bowel rats

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You should have attempted weight loss through diet and exercise without success, and be motivated to make lifestyle changes, including diet and exercise, to support your goals