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These studies often employ daily or twice-daily dosing regimens for periods spanning days to weeks, depending on the condition under investigation, such as tissue repair or gastrointestinal healing

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One is that a subset of patients with uncomplicated diverticulitis are unresponsive to antibiotic therapy as would be expected in the case of a smoldering, focal bowel-wall infection due to diverticular sepsis or microperforation (see below)

neurexin-1 expression level increases with age, neurexin-3 remains stable, and neurexin-2 expression level is higher than that of neurexin-1 and neurexin-2 at early ages [66]