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The set-up of the LC-MS method could be applied experimentally only for vicine (purchased from Sigma), due to the lack of a commercial convicine standard

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Otherwise, we can never achieve consistent clinical outcomes with exogenous antioxidants as monotherapy or as adjuvants with standard cancer therapy in the management of brain cancer

However, immediaterelease gabapentinoids are associated with notable adverse effects including sedation, dizziness, fatigue, weight gain, cognitive impairment, depression, suicidal ideation, and potential risks of misuse, abuse, and respiratory depression [370]