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Description
Cell 171 (3), 628641 e626
Mechanically, the strategy that rewrites itaconate metabolism for achieving additional benefits is primarily dependent on delivering itaconate into macrophages in a locally on-demand manner
SIRT1 activation also promotes fatty acid oxidation, reduces lipogenesis, improves insulin sensitivity, and enhances cellular stress resistance
doi: 10.1177/030089167706300208
