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To establish infection and promote survival, they have evolved diverse strategies to escape lysosomal degradation, including destabilization of lysosomes through LMP or other mechanisms to compromise lysosomal integrity (Figure 2)

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Category 2 substances have been identified as presenting potential safety risks

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In contrast, commensal colonizer lineages, such as cc53, have not acquired these GIs and are characterized by thirteen unique loss-of-function loci (Mullally et al., 2021)

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181 YangH.WuY.MaH.JiangL.ZengX.DanH.et al

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