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This allows the drugs to enter the hair cells through their apical membrane, leading to ototoxic effects

However, NO and ROS can independently release cytochrome c from mitochondria, affecting the caspase-like signalling pathway that leads to HR (Mur et al., 2006)

AD is characterized by neuron degeneration in various cortical regions, leading to progressive memory loss and dementia

doi: 10.1186/1750-1326-8-28 49 ChenQ