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No significant changes in different CER species were detected in MAM isolated from PE and PTC placentae (Supplemental Fig

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For instance, in ALK-positive lung cancer exposed to crizotinib, pre-existing resistant subclones can maintain survival signals through epigenetic reprogramming, allowing them to expand exponentially and eventually dominate the population [8, 9, 215]

Deterioration of CD was classified according to the CD activity index (CDAI) (34), which is a composite scoring system based on selected clinical symptoms, such as the number of liquid stools, the severity of abdominal pain, general well-being, extraintestinal CD manifestations, abdominal mass, use of antidiarrheal drugs, as well as haematocrit and body weight