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[18] Confusion is another possible neurological symptom

Treatment duration at this dose typically ranges from 8-12 weeks, followed by an appropriate off-cycle period

Patients leave the clinic with measurably brighter, more even-toned and visually luminous skin within the same day

Five unique GSTP1 -specific shRNA plasmids (clones TRCN0000083 773 , TRCN0000083 774 , TRCN0000083 775 , TRCN0000083 776 and TRCN0000083 777 ) and a negative control plasmid (empty vector control, SHC001) were purchased as glycerol stocks and plasmid DNA extracted using plasmid DNA maxi prep kits (Qiagen, Manchester, UK) according to the manufacturers instructions