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Mechanisms and outcomes Vitamin B12 interventions are commenced upon diagnosis of low B12 status, typically comprise high dose injections until levels are within acceptable range, and then the intervention is changed to a maintenance dose that is typically administered every 3 months ad infinitum

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Oral B12 supplementation is more accessible and cost-effective but relies on gastric intrinsic factor for absorption, rendering it unsuitable for individuals with gastric disorders or malabsorption syndromes