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TMED4 is a potent activator of NRF2, and loss of TMED4 prevents NRF2 from inducing an antioxidant state within the cell

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VLDL, very low density lipoprotein

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Of course, the time change is real

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While radioprotectant agents have not yet been definitively proven to have measurable clinical benefit, radiation exposure is known to have undesirable clinical sequelae

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