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Research gaps and future prospects Limited clinical validation Despite a wealth of preclinical evidence supporting rhamnetins potential, there is a significant gap in robust clinical trials to validate its safety, efficacy, and optimal dosage in humans

While these options may be more expensive, they are significantly safer

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Sorrenti S., Baldini E., Pironi D., Lauro A., Dorazi V., Tartaglia F., Tripodi D., Lori E., Gagliardi F., Pratic M., et al
