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[230] reported that PSO can reduce the abundance of Escherichia-Shigella by increasing the abundance of the dominant bacterial genera Akkermansia muciniphila and Norank_F_Muribaculaceae , as well as by promoting intestinal bile acid metabolism and increasing the expression of certain bile acid transporters, thereby lowering the levels of inflammatory factors (IL-6, IL-1,and TNF-) and affecting the integrity of the intestinal barrier
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