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In rare cases, pain and swelling may point to bone infections or tumors
Evidence includes: Stimulation of endothelial and keratinocyte migration Enhanced blood vessel density in wound healing models Promotion of stem cell differentiation toward repair cell lineages Low molecular weight enabling tissue penetration over long distances Unlike growth factors that bind to extracellular matrix, TB-500s mobility allows systemic distribution to multiple injury sites
High salinity seawater, generally, sinks below the lower salinity water

No chronic toxicity has been documented in animal research (Vukojevic et al., 2020)
