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[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Center S.A
We discovered that Diphenyleneiodonium chloride (DPI), an inhibitor of flavoprotein enzymes and mitochondrial complex I, synergizes with mitoquinone mesylate (MitoQ), a mitochondria-targeted antioxidant in 2D and 3D in vitro models of NB
Downregulation of the activity of a number of CoA-dependent acyltransferases has been reported in HSL-null mice, and it is believed to contribute to maintenance of normal weight in the face of complete ablation of this important lipolytic enzyme (144)
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