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Of the subset of patients that preferred DTE, it was found that those patients noted a small amount (an average of 4lbs) of weight loss on DTE vs other treatments.5 A Comparison of Concentrations Though evidence does not suggest that DTE or combination levothyroxine/liothyronine products are superior for all patients, the evidence does suggest that some patients may find additional benefit or express a preference for such treatments, while others may prefer synthetic thyroid replacement alone, perhaps due to potentially increased adverse events that could be associated with DTE products.6 Given these differences in preference, patients may switch back and forth between thyroid therapies trying to find the treatment that works best for them

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