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In vitro studies showed that DHLA in addition to Co 2+ , Ni 2+ , Cd 2+ , Cu 2+ , Zn 2+ , Pb 2+ , and Hg 2+ also chelates Fe 3+ (its complex is more stable than that formed with Fe 2+ ), whereas ALA preferentially binds Mn 2+ , Cu 2+, Zn 2+ , and Pb 2+ but cannot chelate Fe 3+ [14,15]

An immediate precursor of NACA called diNACA has recently gained attention for cataract treatment

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Confusion usually starts here people either take far more than any study actually tested, hoping for faster results, or take it inconsistently and stop before the 8-to-12-week mark most trials needed to show change
