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PRMT1 floxed mice (C57BL/6J background, PRMT1fl/fl) were obtained from Shanghai Model Organisms

This research strengthens the advantages derived from dendrimers, such as enhanced structural adaptability, stability, and mucosal penetration, as well as improved drug loading efficiency and sustained drug release (Suthar et al., 2025)

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When combined with Semaglutide in the CagriSema protocol, weight loss exceeded 22%, showing Cagrilintide has strong synergistic potential with the GLP-1 pathway