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Also, some natural products such as berberine allow HIF-1 degradation induction and its anti-angiogenic effects in cancer cells and in endothelial cells [30,95,96,97]

- Lithium: because it reduces the renal clearance and increases lithium levels in plasma which increases the risk of lithium toxicity

zdemir et al., 2016

In two studies in rats, no teratology was observed when 512 mg/kg of sulfamethoxazole was used in combination with 128 mg/kg of trimethoprim
