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Because of suprasellar extension, pituitary tumours may interrupt dopamine delivery from the hypothalamus to the pituitary, resulting in loss of inhibition of prolactin release, or the stalk effect. In contrast, tumours that produce growth hormone (GH) may also secrete prolactin in nearly 25% of cases.2 This is a common source of misdiagnosis, as the features of prolactin excess may capture attention while the more subtle features of GH excess go unnoticed

Both transporters are also reported to be internalized in response to pretreatment with AMPH [2, 6], but it whether they are regulated through the same mechanism remains unclear

127 RajagopalA.RaoA

( D ) Influence of ETHE1 depletion on the loss of viability of HeLa cells treated with either RSL3 (5 M) (left panels) or CHP (40 M) (right panels), measured with the CellTox Green cytotoxicity assay