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4 The regulatory role of gut microbiota dysbiosis in the pathogenesis of IBD Clinical data indicate a significant positive correlation between gut microbiota dysbiosis and the onset and progression of IBD, manifested specifically as reduced -diversity, depletion of commensal probiotic bacteria, and abnormal proliferation of pro-inflammatory pathogens (83)

168,169 The indomethacin-induced gastric ulcers in mice were suppressed by the aqueous leaf extract of Jamun, which also attenuated TNF-, NF-B, iNOS, COX1, and COX2 expression

Compounded tirzepatide became severely restricted after the FDA removed it from the drug shortage list in December 2024

[DOI] [PMC free article] [PubMed] [Google Scholar] 49.Zhu F., Guo R., Wang W., Ju Y., Wang Q., Ma Q., Sun Q., Fan Y., Xie Y., Yang Z., et al