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Early research suggested that glucose could directly stimulate excessive ROS production (Rizwan et al., 2020), including the activation of NADPH oxidase (Jansen et al., 2013), NO synthase uncoupling (Sasaki et al., 2008), and the stimulation of xanthine oxidase (Hernandez-Hernandez et al., 2022)

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This paper is the winner of an SFB Award in the Hospital Intern, Residency category: Peptide biomaterials raising adaptive immune responses in wound healing contexts

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